Human CD11a Monoclonal Antibody, Endotoxin 0.05 EU/mg
Biozol Catalog Number:
ABB-YR0112
Supplier Catalog Number:
YR0112
Alternative Catalog Number:
ABB-YR0112-5MG,ABB-YR0112-20MG
Manufacturer:
ABclonal
Category:
Antikörper
Application:
ELISA, NeA
Immunogen:
Human CD11a
Alternative Names:
CD11A, LFA-1, LFA1A
Efalizumab is a monoclonal anti-CD11a antibody used to treat moderate to severe plaque psoriasis.Humanized IgG1 kappa isotype monoclonal antibody that binds to human CD11a. Efalizumab has a molecular weight of approximately 150 kilodaltons and is produced in a Chinese hamster ovary mammalian cell expression system in a nutrient medium containing the antibiotic gentamicin.Efalizumab binds to CD11a, a subunit of leukocyte function antigen-1 (LFA-1), which is expressed on all leukocytes. As a result efalizumab decreases cell surface expression of CD11a.
