In vivo Grade Recombinant Anti-mouse TIGIT Monoclonal Antibody (Clone: 10A7), Mouse IgG2a Kappa

Product Overview

• Article Name: In vivo Grade Recombinant Anti-mouse TIGIT Monoclonal Antibody (Clone: 10A7), Mouse IgG2a Kappa
• Biozol Catalog Number: ABB-YR0382
• Supplier Catalog Number: YR0382
• Alternative Catalog Number: ABB-YR0382-1MG, ABB-YR0382-5MG, ABB-YR0382-25MG
• Manufacturer: ABclonal
• Category: Antikörper
• Application: ELISA, FC, NeA

Product Description

The 10A7 antibody binds to the TIGIT protein (WUCAM, Vstm3 or VSIG9), a novel immune checkpoint receptor with inhibitory function. TIGIT is expressed on T cells and natural killer (NK) cells, and several human cancers, including melanoma, NSCLC, and colorectal cancer. Similar to PD-1, the TIGIT receptor limits antitumor immune response in cancer.

Product Properties

• Purity: >95% Determined by SDS-PAGE

Application Notes

• Application Notes: Cross-Reactivity: <1EU/mg (<0.001EU/µg)Determined by LAL gel clotting assay