In vivo Grade Recombinant Anti-mouse CD28 Monoclonal Antibody, Syrian Hamster IgG2 (Clone: 37.51)

Product Overview

• Article Name: In vivo Grade Recombinant Anti-mouse CD28 Monoclonal Antibody, Syrian Hamster IgG2 (Clone: 37.51)
• Biozol Catalog Number: ABB-YR0385
• Supplier Catalog Number: YR0385
• Alternative Catalog Number: ABB-YR0385-5MG, ABB-YR0385-1MG, ABB-YR0385-25MG
• Manufacturer: ABclonal
• Category: Antikörper
• Application: ELISA, FC, NeA

Product Description

The in vivo grade recombinant hamster monoclonal antibody (clone: 37.51) specifically binds to the mouse CD28 protein. CD28 is a critical costimulatory receptor belonging to the immunoglobulin superfamily. Upon binding to its ligands CD80 (B7-1) and CD86 (B7-2)-expressed on antigen-presenting cells (APCs)-CD28 triggers intracellular signaling cascades that promote T cell proliferation, cytokine production, and the survival of activated T cells. Dysregulation of CD28 signaling is linked to autoimmune diseases, immune deficiency, and impaired antitumor immunity, making it a central target for studying immune activation and modulation in murine models.

Product Properties

• Purity: >95% Determined by SDS-PAGE

Application Notes

• Application Notes: Cross-Reactivity: <1EU/mg (<0.001EU/µg)Determined by LAL gel clotting assay