Related studies have shown that M252Y/S254T/T256E (YTE) mutations in the Fc region of IgG antibodies can prolong the half-life of therapeutic antibodies, optimize the pharmacokinetic characteristics, and reduce the frequency of administration. We developed Rabbit Anti-human IgG-FC (YTE mutation) Specific Monoclonal Antibody that effectively captures and stably binds to IgG Fc segment YTE mutants. The YTE mutant for therapeutic IgG has important application value in pharmacodynamic/pharmacokinetic studies and detection technology.
Purity:
>95% Determined by SDS-PAGE
Application Notes:
Cross-Reactivity: <1EU/mg (<0.001EU/µg)Determined by LAL gel clotting assay
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