Non-nucleosidic modifier reagent for the synthesis of biotinylated oligos based on a hydroxyprolinol core. This phosphoramidite contains a dimethoxytrityl protective group for the purification of the resulting oligos on C18 cartridges, and reverse phase HPLC. This modifier reagent can be used to introduce biotin onto 5-position, 3-position (using universal CPG), and internal oligo sites. This amidite does not require special condensation and deprotection conditions.
Molecular Weight:
959.18 kDa
Purity:
95% (by 1H and 31P NMR, HPLC-MS, and functional testing in oligo synthesis).
Form:
White powder.
Formula:
C51H71N6O8PS
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