TCO (tetrazine - trans-cyclooctene) ligation is one of the fastest reactions used for bioconjugation. It is an inverse electron demand [4+2] cycloaddition that takes place between tetrazine and trans-cyclooctene or other strained olefin. Sulfo-Cyanine 5 tetrazine is a fluorophore derivative bearing a tetrazine group for the TCO-ligation based labeling. This reagent possesses good aqueous solubility and stability in biological environments.
Molecular Weight:
864.09 Da
Purity:
95% (by 1H NMR and HPLC-MS).
Form:
Dark blue solid.
Formula:
C42H46KN7O7S2
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