NALE(TM) Monoclonal Antibody to TLR7 (Clone: ABM2C27)

Product Overview

• Article Name: NALE(TM) Monoclonal Antibody to TLR7 (Clone: ABM2C27)
• Biozol Catalog Number: ABI-10-3015-NALE
• Supplier Catalog Number: 10-3015-NALE
• Alternative Catalog Number: ABI-10-3015-NALE-100UG
• Manufacturer: Abeomics
• Host: Mouse
• Category: Antikörper
• Application: FACS, IHC
• Species Reactivity: Human
• Immunogen: A partial length recombinant human TLR7 protein (amino acids 500-900) was used as the immunogen for this antibody.
• Alternative Names: TLR7||UNQ248/PRO285

Product Description

TLR7 (Toll-like receptor 7) is a member of the Toll-like receptor (TLR) family. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR7 controls host immune response against pathogens through recognition of molecular patterns specific to microorganisims. TLR7 interacts with MYD88 via their respective TIR domains and also interacts with UNC93B1. Post-translational modifications and glycosylation occur in TLR7. TLR7 detected in brain, placenta, spleen, stomach, small intestine, lungs and plasmacytoid pre-dendritic cells.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [ABM2C27]
• NCBI: 51284
• UniProt: Q9NYK1
• Purity: Protein G Chromatography
• Form: Azide Free,Purified
• Target: TLR7

Application Notes

• Application Dilute: FACS analysis: 0.5 µg/10 6 cells, Immunohistochemical analysis: 5 µg/ml

Images

Fig-1 : Immunohistochemical analysis of TLR7 in human Kidney tissue using TLR7 antibody (Clone: ABM2C27) at 5 µg/ml.

Fig-2: Intracellular flow analysis of TLR7 in PBMC (Lymphocyte) using 0.5 µg/10 6 cells of TLR7 antibody (Clone: ABM2C27). Green represents isotype control, red represents anti-TLR7 antibody. Goat anti-mouse PE conjugate was used as secondary.

Fig-3:Immunohistochemical analysis of TLR7 in Renal Cell Carcinoma using TLR7 antibody (Clone: ABM2C27) at 5 µg/ml.

Fig-4: Intracellular flow analysis of TLR7 in Raji cells using 0.5 µg/10 6 cells of TLR7 antibody (Clone: ABM2C27). Green represents isotype control, red represents anti-TLR7 antibody. Goat anti-mouse PE conjugate was used as secondary antibody.