NALE(TM) Monoclonal Antibody to TLR2 (Clone: ABM3A87)

Product Overview

• Article Name: NALE(TM) Monoclonal Antibody to TLR2 (Clone: ABM3A87)
• Biozol Catalog Number: ABI-10-3026-NALE
• Supplier Catalog Number: 10-3026-NALE
• Alternative Catalog Number: ABI-10-3026-NALE-100UG
• Manufacturer: Abeomics
• Host: Mouse
• Category: Antikörper
• Application: FACS, IHC, WB
• Species Reactivity: Human, Mouse
• Immunogen: A partial length recombinant TLR2 protein (amino acids 180-420) was used as the immunogen for this antibody.
• Alternative Names: TLR2||TIL4

Product Description

TLR2 (Toll-Like Receptors 2) is a member of the TLR (Toll-like receptor) family that plays a fundamental role in pathogen recognition and activation of innate immunity. TLR2 forms heterodimers with TLR1 and TLR6, which is the initial step in a cascade of events leading to significant innate immune responses, development of adaptive immunity to pathogens and protection from immune sequelae related to infection with these pathogens. TLR2 also interacts with a large number of non-TLR molecules, allowing for recognition of a great number and variety of PAMPs (pathogen-associated molecular patterns). TLR2 expression has been detected in immune cells, endothelial, and epithelial cells.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [ABM3A87]
• NCBI: 7097
• UniProt: O60603
• Purity: Protein G Chromatography
• Form: Azide Free,Purified
• Target: TLR2

Application Notes

• Application Dilute: Western blot analysis: 2-4 µg/ml, FACS analysis: 0.5 µg/10 6 cells, Immunohistochemical analysis: 5 µg/ml

Images

Fig-6: Immunohistochemical analysis of TLR2 in human Colon tissue using TLR2 antibody (Clone: ABM3A87) at 10 µg/ml.

Fig-1: Western blot analysis of TLR2. Anti- TLR2 antibody (Clone: ABM3A87) was used at 2 µg/ml on mouse embryonic liver lysate.

Fig-2 : Immunohistochemical analysis of TLR2 in human prostate tissue using TLR2 antibody (Clone: ABM3A87) at 5 µg/ml.

Fig-3: Intracellular flow analysis of TLR2 in PBMC (Monocytes) using 0.5 µg/10 6 cells of TLR2 antibody (Clone: ABM3A87). Green represents isotype control, red represents anti-TLR2 antibody. Goat anti-Mouse PE conjugate was used as secondary.

Fig-5: Immunohistochemical analysis of TLR2 in Renal Cell Carcinoma using TLR2 antibody (Clone: ABM3A87) at 5 µg/ml.

Fig-4: Intracellular flow analysis of TLR2 in THP-1 cells using 0.5 µg/10 6 cells of TLR2 antibody (Clone: ABM3A87). Green represents isotype control, red represents anti-TLR2 antibody. Goat anti-Mouse PE conjugate was used as secondary antibody.