Monoclonal Antibody to mCD11c (Clone: ABM-N418), Clone: [ABM-N418], Hamster
Catalog Number:
ABI-10-4124-25
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| Article Name: | Monoclonal Antibody to mCD11c (Clone: ABM-N418), Clone: [ABM-N418], Hamster |
| Biozol Catalog Number: | ABI-10-4124-25 |
| Supplier Catalog Number: | 10-4124-25 |
| Alternative Catalog Number: | ABI-10-4124-25-25UG |
| Manufacturer: | Abeomics |
| Host: | Hamster |
| Category: | Antikörper |
| Application: | FACS |
| Alternative Names: | CD11 antigen-like family member C, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150,95, Integrin alpha-X |
| CD11c/CD18 ( p150/95, or complement receptor 4, CR4) is a monocyte/macrophage-enriched integrin that has been reported to bind to a variety of ligands. These include cell surface proteins (LPS, ICAM-1, ICAM-2, ICAM-4 and VCAM-1), extracellular matrix proteins (collagen I), and soluble ligands (iC3b, heparin and fibrinogen). It is expressed in macrophages, monocytes, granulocytes, subsets of T and B cells, and dendritic cells. CD11c functions as a cell surface receptor for numerous soluble factors and proteins. The interaction mediates leukocyte interactions with other cell types and is a signal transducing receptor. It is found primarily on myeloid cells, where its expression is regulated both during differentiation and during monocyte maturation into tissue macrophages. |
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