Polyclonal Antibody to SARS-CoV-2 nucleocapsid Protein, Rabbit

Product Overview

• Article Name: Polyclonal Antibody to SARS-CoV-2 nucleocapsid Protein, Rabbit
• Biozol Catalog Number: ABI-11-2004-25
• Supplier Catalog Number: 11-2004-25
• Alternative Catalog Number: ABI-11-2004-25-25UG
• Manufacturer: Abeomics
• Host: Rabbit
• Category: Antikörper
• Application: ELISA, WB
• Immunogen: SARS-CoV-2/COVID-19 Nucleocapsid (Ser2-Ala419) with His-tag in N-terminal was used as the immunogen for this antibody.
• Alternative Names: sars-cov-2

Product Description

The structural nucleocapsid (N) protein of nCoV/SARS-CoV-2/COVID-19 is a predicted 46 kDa phosphoprotein having 419 amino acid residues. A short Serine rich stretch and a recognized nuclear localization signal are the unique features of the nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19, which seems to have a little homology with the proteins of other members of this large corona virus family. These features also suggest the involvement of nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19 in different stages of viral lifecycle. The protein has multifaceted activities including packing of the nCoV/SARS-CoV-2/COVID-19 viral genome into a helical ribonucleocapsid (RNP) and playing an important role in viral self-assembly causing nCoV/SARS-CoV-2/COVID-19. The nucleocapsid protein of nCoV/SARS-CoV-2/COVID-19 also forms dimer in the cell by self-association with the help of interactive C terminal domain.

Product Properties

• Clonality: Polyclonal
• Purity: Protein A Chromatography
• Form: Purified
• Target: Nucleocapsid
• Antibody Type: Polyclonal Antibody

Application Notes

• Application Dilute: Recommended dilutions: WB: 1-2 µg/ml. However, this need to be optimized based on the research applications.

Images

Figure-1: Western Blot analysis of SARS-CoV-2 Nucleocapsid Protein: Anti- SARS-CoV-2 Nucleocapsid Protein (11-2004) was used at 2 µg/ml on (1) SARS-CoV-2 virus infected Vero Cell lysate and (2) Mock infected lysate.

Figure-2: Western Blot analysis of Nucleocapsid antibody (SARS-CoV-2): Anti- Nucleocapsid antibody (SARS-CoV-2) was used at 1 µg/ml on recombinant Nucleocapsid Protein (Cat21-1003).