Recombinant Mouse Monoclonal Antibody to Cytokeratin 7 (Glandular and Transitional Epithelial Marker)(Clone : rOV-TL12/30), Clone: [rOV-TL12/30]
Biozol Catalog Number:
ABI-12-1005-20
Supplier Catalog Number:
12-1005-20
Alternative Catalog Number:
ABI-12-1005-20-20UG
Manufacturer:
Abeomics
Category:
Sonstiges
Application:
FACS, IHC, WB
Species Reactivity:
Human
Immunogen:
OTN 11, ovarian carcinoma cell line
Alternative Names:
CK-7, K2C7, Keratin 55K Type II Cytoskeletal, Keratin Simple Epithelial Type 1 K7, Keratin Type II Cytoskeletal 7, Krt2-7, KRT7, Sarcolectin, SCL, Type II Mesothelial Keratin K7, Type-II Keratin Kb7
It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-).
Cytokeratin 7 (Glandular and Transitional Epithelial Marker)
Antibody Type:
Recombinant Antibody
Application Dilute:
Western Blot (1-2µg/ml), Flow Cytometry (1-2µg/million cells), Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&a
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