Anti-Cytokeratin, Multi (Epithelial Marker) Recombinant Mouse Monoclonal Antibody (Clone:rKRT/457), Clone: [rKRT/457]

Product Overview

• Article Name: Anti-Cytokeratin, Multi (Epithelial Marker) Recombinant Mouse Monoclonal Antibody (Clone:rKRT/457), Clone: [rKRT/457]
• Biozol Catalog Number: ABI-12-1166-20
• Supplier Catalog Number: 12-1166-20
• Alternative Catalog Number: ABI-12-1166-20-20UG
• Manufacturer: Abeomics
• Host: Mouse
• Category: Sonstiges
• Application: IHC
• Species Reactivity: Human
• Immunogen: Keratin-enriched preparation from cultured human epithelial cells

Product Description

Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI<5.7) and basic (pI>6.0) subfamilies. This antibody recognizes acidic (Type I or LMW) and basic (Type II or HMW) cytokeratins, including 59kDa (CK4), 58kDa (CK5), 56kDa (CK6), 52kDa (CK8), 56.5kDa (CK10), 53kDa (CK13) and 45kDa (CK18). This is a broad-spectrum antibody, which has been reported to differentiate epithelial tumors from non-epithelial tumors. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [rKRT/457]
• NCBI: 3851
• UniProt: P02538
• Purity: Protein A/G
• Form: Purified
• Antibody Type: Recombinant Antibody

Application Notes

• Application Dilute: Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes)