A synthetic phospho-peptide corresponding to residues surrounding Tyr641 of human phospho Stat6
Conjugation:
Unconjugated
Alternative Names:
Signal transducer and activator of transcription 6, IL-4 Stat
The transcription factor Stat6 is a member of the signal transducers and activators of transcription (STAT) family of proteins. Stat6 is the only member of this family that is activated by interleukin-4 (IL-4), after which Stat6 is both tyrosine- and serine-phosphorylated by Jak kinases. The consensus Stat6 binding site TTCN4GAA is found in the promoters of many genes regulated by IL-4. In T lymphocytes, Stat6 is required for differentiation into Th2 cells in response to IL-4. Stat6 may play a role in solid tumorigenesis, a large immunohistochemistry study of Stat6 expression in over 2,000 tumor samples confirmed strong nuclear staining.
Clonality:
Monoclonal
Clone Designation:
[Stat6Y641-G12]
Form:
Purified
Application Dilute:
1µg/mL - 0.001µg/mL. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information.(0.5mg/ml, more than 200 western blots)
* VAT and and shipping costs not included. Errors and price changes excepted
