A synthetic phospho-peptide corresponding to residues surrounding Thr37/46 of human phospho 4E-BP1.
Conjugation:
Unconjugated
Alternative Names:
Eukaryotic translation initiation factor 4E-binding protein 1, eIF4E-binding protein 1, PHAS-I, EIF4EBP1
4E-BP1 regulates protein translations induced by upstream signals initiated by ERK1/2 MAP kinase or PI3-Kinase/AKT/mTOR pathways. Ultimately activation of mTOR, positively stimulates mRNA translation by its two dominant downstream substrates: ribosomal p
Clonality:
Monoclonal
Clone Designation:
[4EB1T37T46-A5]
Isotype:
Rabbit IgG1k
Buffer:
1X PBS, 0.02% NaN3, 50% Glycerol, 0.1% BSA
Form:
Purified
Application Dilute:
1µg/mL - 0.001µg/mL. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information.(0.5mg/ml, more than 200 western blots)
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