Phospho-PLCg1 (Tyr783) (Clone: C4) rabbit mAb, Clone: [PLCG1Y783-C4], Unconjugated, Rabbit, Monoclonal

Product Overview

• Article Name: Phospho-PLCg1 (Tyr783) (Clone: C4) rabbit mAb, Clone: [PLCG1Y783-C4], Unconjugated, Rabbit, Monoclonal
• Biozol Catalog Number: ABI-12-4096
• Supplier Catalog Number: 12-4096
• Alternative Catalog Number: ABI-12-4096-200UL
• Manufacturer: Abeomics
• Host: Rabbit
• Category: Antikörper
• Application: FACS
• Species Reactivity: Human
• Immunogen: A synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCg1.
• Conjugation: Unconjugated
• Alternative Names: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, PLC-148, Phosphoinositide phospholipase C-gamma-1, Phospholipase C-II, Phospholipase C-gamma-1, PLC-gamma-1, PLC1

Product Description

The Phospholipase C (PLC) isozymes hydrolyze phosphatidyl inositolphosphate to inositol triphosphate and diacylglycerol. In response to extracellular stimuli such as hormones, growth factors and neurotransmitters, PLC hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2) to generate diacylglycerols (DAGs) and water-soluble phosphorylated derivatives, such as inositol 1,4,5-triphosphate (IP3). Within the PLC family, PLCg is the only member that contains SH2 and SH3 domains, necessary for phospho PLCg activation. Phospho PLCg, upon activation, can interact with receptor tyrosine kinases.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [PLCG1Y783-C4]
• Form: Purified

Application Notes

• Application Dilute: 1µg/mL - 0.001µg/mL. It is recommended that the reagent be titrated for optimal performance for each application. See product image legends for additional information.(0.5mg/ml)