Recombinant SARS-CoV-2 Nucleocapsid (Met1-Ala 419) produced by using E. coli
Alternative Names:
SARS-CoV-2 Nucleocapsid
Coronavirus contain most of nucleocapsid protein. Coronavirus nucleoproteins (N proteins) localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. The nucleolus is the site of ribosome biogenesis and sequesters cell cycle regulatory complexes. Two of the major components of the nucleolus are fibrillarin and nucleolin. These proteins are involved in nucleolar assembly and ribosome biogenesis and act as chaperones for the import of proteins into the nucleolus. Regarding of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is a tool for diagnostic.
Clonality:
Monoclonal
Clone Designation:
[DM22]
Purity:
Purified from cell culture supernatant by affinity chromatography
Antibody Type:
Monoclonal Antibody
Application Dilute:
Recommended Dilutions ELISA 1/5000-1/10000
Figure 1. Elisa plate pre-coated by 2 µg/ml(100µl/well) SARS-CoV-2 Nucleocapsid protein, His Tag can bind Rabbit Anti-SARS-CoV-2 Nucleocapsid monoclonal antibody(clone:DM22) in a linear range of 0.24-62.5 ng/ml.
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