TNF-alpha Leeporter(TM) Luciferase Reporter-HEK293 Cell Line Preis auf Anfrage
Biozol Catalog Number:
ABI-14-105ACL
Supplier Catalog Number:
14-105ACL
Alternative Catalog Number:
ABI-14-105ACL-1VIAL
Manufacturer:
Abeomics
Category:
Zellen/Zellkultur
Application:
FA
The TNF-alpha Leeporter(TM) Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the TNF-alpha promoter. Tumor necrosis factor-alpha (TNF-alpha) is one of the major proinflammatory cytokines and can induce systemic inflammation, apoptotic cell death, sepsis and cachexia. Dysregulation of TNF-alpha induction is often involved in various human diseases including inflammatory bowel disease, cancer and Alzheimers disease. The TNF-alpha induction by phorbol 12-myristate 13-acetate (PMA) is shown in Figure 1.
Application Dilute:
Application: Monitor the TNF-alpha induction activity. Screen for activators or inhibitors of the TNF-alpha signaling pathway. Culture conditions: Cells should be grown at 37C with 5% CO2 using DMEM medium (w/ L-Glutamine, 4.5g/L Glucose and Sodium Pyruva
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