TNF-beta Leeporter(TM) Luciferase Reporter-RAW264.7 Cell Line Preis auf Anfrage

Product Overview

• Article Name: TNF-beta Leeporter(TM) Luciferase Reporter-RAW264.7 Cell Line Preis auf Anfrage
• Biozol Catalog Number: ABI-14-108ACL
• Supplier Catalog Number: 14-108ACL
• Alternative Catalog Number: ABI-14-108ACL-1VIAL
• Manufacturer: Abeomics
• Category: Zellen/Zellkultur
• Application: FA

Product Description

The TNF-beta Leeporter(TM) Luciferase Reporter cell line is a stably transfected RAW264.7 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the TNF-beta promoter. Tumor necrosis factor-beta (TNF-beta) one of the major proinflammatory cytokines, which is produced predominantly by mitogen-stimulated T lymphocytes and leukocytes. TNF-beta is involved in the regulation of various biological processes such as cell proliferation, differentiation and apoptosis. TNF-beta gene polymorphisms are also significantly associated with disease susceptibility and phenotype in patients with psoriatic arthritis. The TNF-beta induction by lipopolysaccharide (LPS), the Toll-like receptor 4 (TLR4) ligand, is shown in Figure 1.

Application Notes

• Application Dilute: Application: Monitor the TNF-beta induction activity. Screen for activators or inhibitors of the TNF-beta signaling pathway. Culture conditions: Cells should be grown at 37C with 5% CO2 using DMEM medium (w/ L-Glutamine, 4.5g/L Glucose and Sodium Pyruvate