TLR4/IL-8 Leeporter(TM) Luciferase Reporter-HeLa Cell Line Preis auf Anfrage

Product Overview

• Article Name: TLR4/IL-8 Leeporter(TM) Luciferase Reporter-HeLa Cell Line Preis auf Anfrage
• Biozol Catalog Number: ABI-14-124ACL
• Supplier Catalog Number: 14-124ACL
• Alternative Catalog Number: ABI-14-124ACL-1VIAL
• Manufacturer: Abeomics
• Category: Zellen/Zellkultur
• Application: FA

Product Description

The TLR4/IL-8 Leeporter(TM) Luciferase Reporter cell line is a stably transfected HeLa cell line which expresses human TLR4, MD-2 and CD14 as well Renilla luciferase reporter gene under the transcriptional control of the IL-8 promoter. IL-8 is one of the major pro-inflammatory cytokines induced by ligand (such as LPS)-mediated Toll-like receptor 4 (TLR4) activation. TLR4 is one of the key innate immune receptors, which is activated by LPS and can lead to sepsis upon dysregulation. The TLR4/IL-8 activation by LPS is shown in Figure 1.

Application Notes

• Application Dilute: Application: Monitor the TLR4 signaling pathway activity. Screen for activators or inhibitors of the TLR4 signaling pathway. Culture conditions: Cells should be grown at 37C with 5% CO2 using DMEM medium (w/ L-Glutamine, 4.5g/L Glucose and Sodium Pyruvate