MRE Leeporter(TM) Luciferase Reporter HEK293 Cell Line Preis auf Anfrage
Biozol Catalog Number:
ABI-14-137ACL
Supplier Catalog Number:
14-137ACL
Alternative Catalog Number:
ABI-14-137ACL-1VIAL
Manufacturer:
Abeomics
Category:
Zellen/Zellkultur
Application:
FA
The MRE Leeporter(TM) Luciferase Reporter cell line is a stably transfected HEK 293 cell line which expresses Renilla luciferase reporter gene under the transcriptional control of the metal response element (MRE). MRE is targeted by MRE-binding transcription factor-1 (MTF-1) which is a zinc finger transcription factor and plays a major role in induction of metallothionein gene expression in response to cellular stress caused by heavy metals such as zinc and cadmium. The MRE induction by ZnSO4 is shown in Figure 1.
Application Dilute:
Application: Monitor MTF-1 transcriptional activity. Screen for activators or inhibitors of the MTF-1 signaling pathway. Culture conditions: Cells should be grown at 37C with 5% CO2 using DMEM medium (w/ L-Glutamine, 4.5g/L Glucose and Sodium Pyruvate) su
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