TLR3/NF-kB Leeporter(TM) GFP Reporter-HEK293 Cell Line Preis auf Anfrage
Biozol Catalog Number:
ABI-14-701ACL
Supplier Catalog Number:
14-701ACL
Alternative Catalog Number:
ABI-14-701ACL-1VIAL
Manufacturer:
Abeomics
Category:
Zellen/Zellkultur
Application:
FA
The TLR3/NF-kB Leeporter(TM) GFP Reporter cell line is a stably transfected HEK293 cell line, which expresses full-length human Toll-like receptor 3 (TLR3) and enhanced green fluorescent protein (eGFP) reporter gene under the transcriptional control of the NF-kB response element. Functional activity of the cell line has been validated by TLR3 ligand assay, in which upon activation by poly (I:C), TLR3 quickly initiates TRIF-dependent signaling pathway and mediates nuclear translocation of NF-kB (Figures 1 and 2).
Application Dilute:
Application: Monitor the TLR3 signaling pathway. Screen for activators or inhibitors of the TLR3 signaling pathway. Culture conditions: Cells should be grown at 37oC with 5% CO2 using DMEM medium (w/ L-Glutamine, 4.5g/L Glucose and Sodium Pyruvate) supple
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