Source : Rice Grain (Oryza Sativa). FGF-2 Human Recombinant produced in rice is a single, non-glycosylated polypeptide chain containing 146 amino acids and having a molecular mass of ~17kDa.The FGF-b protein is purified by proprietary chromatographic techniques. Basic fibroblast growth factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. Three alternatively spliced variants encoding different isoforms have been described. The heparin-binding growth factors are angiogenic agents in vivo and are potent mitogens for a variety of cell types in vitro. There are differences in the tissue distribution and concentration of these 2 growth factors.
Purity:
Greater than 95.0% as determined by SDS-PAGE.
Antibody Type:
Recombinant Antibody
Application Dilute:
It is recommended to reconstitute the lyophilized Fibroblast Growth Factor Basic in sterile 18MO-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. The ED50, as calculated by the dose-dependent proliferation of Ba
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