Recombinant Human ACE2 Protein with N-terminal6A-His tag

Catalog Number: ABI-32-17130
Article Name: Recombinant Human ACE2 Protein with N-terminal6A-His tag
Biozol Catalog Number: ABI-32-17130
Supplier Catalog Number: 32-17130
Alternative Catalog Number: ABI-32-17130-50UG
Manufacturer: Abeomics
Category: Proteine/Peptide
Alternative Names: ACE-2,ACEH,ACE2
Expression Host : HEK293 The protein has a predicted molecular mass of 84.4 kDa after removal of the signal peptide. The apparent molecular mass of His-ACE2 is approximately 10-130 kDa due to glycosylation. The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Antibody Type: Recombinant Antibody