Molecular Characterization: PGLYRP1 (Gln22-Pro196) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 45.6 kDa after removal of the signal peptide. The apparent molecular mass of PGLYRP1-hFc is approximately 35-55 kDa due to glycosylation.Description: Recombinant human PGLYRP1 Protein with C-terminal Human Fc tagPattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.[UniProtKB/Swiss-Prot Function]
