Molecular Characterization: Mouse PGLYRP1(Phe19-Glu182) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 44.8 kDa after removal of the signal peptide. The apparent molecular mass of mPGLYRP1-hFc is approximately 35-55 kDa due to glycosylation.Description: Recombinant mouse PGLYRP1 protein with C-terminal human Fc tagPattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria. Involved in innate immunity. May function in intracellular killing of bacteria. The soluble form triggers apoptosis in vitro.[UniProtKB/Swiss-Prot Function]
