Molecular Characterization: CXCR7(Met1-Lys40) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 31.0 kDa after removal of the signal peptide. The apparent molecular mass of CXCR7-hFc is approximately 35-55 kDa due to glycosylation.Description: Recombinant human CXCR7 protein with C-terminal human Fc tagThis gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas.
