Molecular Characterization: IL1RAP(Ser21-Glu359)6A-His tagMolecular weight: The protein has a predicted molecular mass of 39.9 kDa after removal of the signal peptide. The apparent molecular mass of IL1RAP-His is approximately 55-70 kDa due to glycosylation.Description: Recombinant human IL1RAP protein with C-terminal6A-His tagThis gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.
