Molecular Characterization: PDGFD(Ser250-Arg370) hFc(Glu99-Ala330)Molecular weight: The protein has a predicted molecular mass of 40.1 kDa after removal of the signal peptide. The apparent molecular mass of PDGFD(250-370)-hFc is approximately 35-55 kDa due to glycosylation.Description: Recombinant Human PDGFD Protein with C-terminal human Fc tagThe protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene.
