Recombinant Hepatitis C Virus Nucleocapsid (core) 22kDa, Fluorescein Labeled
Biozol Catalog Number:
ABI-32-5428
Supplier Catalog Number:
32-5428
Alternative Catalog Number:
ABI-32-5428-0.5MG
Manufacturer:
Abeomics
Category:
Proteine/Peptide
Source : The E.coli derived recombinant protein contains the HCV core nucleocapsid immunodominant regions, amino acids 2-192. The Fluorescein labeled protein is fused with b-galactosidase (114 kDa) at N-terminus. HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the hosts immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Purity:
HCV-Core protein is >95% pure as determined by 10% PAGE (coomassie staining).
Antibody Type:
Recombinant Antibody
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