HEXA Human, Sf9

Product Overview

• Article Name: HEXA Human, Sf9
• Biozol Catalog Number: ABI-32-6802-2
• Supplier Catalog Number: 32-6802-2
• Alternative Catalog Number: ABI-32-6802-2-2UG
• Manufacturer: Abeomics
• Category: Proteine/Peptide
• Alternative Names: Hexosaminidase A (Alpha Polypeptide), N-Acetyl-Beta-Glucosaminidase Subunit Alpha, Beta-N-Acetylhexosaminidase Subunit Alpha, Hexosaminidase Subunit A, EC 3.2.1.52, TSD, Beta-Hexosaminidase Subunit Alpha, GM2 Gangliosidosis, Tay Sachs Disease, EC 3.2.1, Beta-hexosaminidase subunit alpha, Beta-N-ace

Product Description

Source: Sf9, Baculovirus cells.Sterile Filtered colorless solution.HEXA is the alpha subunit of the lysosomal enzyme beta-hexosaminidase which, combined with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules having N-acetyl hexosamines terminus. The two subunits composing Beta-hexosaminidase, alpha and beta, belong to the glycosyl hydrolases family and are encoded by distinct genes. Alpha subunit gene mutations can cause Tay-Sachs disease (GM2-gangliosidosis type I).HEXA produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 513 amino acids (23-529a.a.) and having a molecular mass of 59.2kDa. (Molecular size on SDS-PAGE will appear at approximately 50-70kDa).

Product Properties

• Purity: Greater than 90% as determined by SDS-PAGE.