Source: Sf9, Baculovirus cells.Sterile Filtered colorless solution.KLK7 catalyzes the degradation of intercellular cohesive structures in the cornified layer of the skin in the continuous shedding of cells from the skin surface. Specific for amino acid residues with aromatic side chains in the P1 position. KLK7 cleaves insulin B chain at 6-Leu- -Cys-7, 16-Tyr- -Leu-17, 25-Phe- -Tyr-26 and 26-Tyr--Thr-27. KLK7 is involved in the activation of precursors to inflammatory cytokines.KLK7 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 190 amino acids (1-181 a.a.) and having a molecular mass of 20.9kDa (Migrates at 28-40kDa on SDS-PAGE under reducing conditions).
Purity:
Greater than 95.0% as determined by SDS-PAGE.
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