MME Human, Active

Product Overview

• Article Name: MME Human, Active
• Biozol Catalog Number: ABI-32-6845-2
• Supplier Catalog Number: 32-6845-2
• Alternative Catalog Number: ABI-32-6845-2-2UG
• Manufacturer: Abeomics
• Category: Proteine/Peptide
• Application: FA
• Alternative Names: Membrane Metalloendopeptidase, Common Acute Lymphocytic Leukemia Antigen, Neutral Endopeptidase 24.11, Skin Fibroblast Elastase, Neutral Endopeptidase, Atriopeptidase, Enkephalinase, EC 3.4.24.11, Neprilysin, CALLA, NEP, SFE,Membrane Metallo-Endopeptidase (Neutral Endopeptidase, Enkephalinase, CALL

Product Description

Source: Sf9, Baculovirus cells.Sterile Filtered colorless solution.Neutral endopeptidase (NEP) is an enzyme located in the cell membrane (bound to it) that is able to dissolve biologically active proteins and is expressed on the surface of lymphoid progenitors, human podocytes, syncytiotrophoblastic cells, and many other epithelial cells including polymorphonuclear leukocytes.MME Human produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 708 amino acids (52-750 aa) and having a molecular mass of 80.9kDa.MME is fused to a 6 amino acid His tag at C-terminus and purified by proprietary chromatographic techniques.

Product Properties

• Purity: Greater than 95.0% as determined by SDS-PAGE.

Application Notes

• Application Dilute: Specific activity > 5,000 pmol/min/ug. One unit will convert 1.0 pmole of Mca-SEVNLDAEFRK(Dnp)RR-NH2 to MCA- Pro-Leu-OH per minute, at pH 8.8 at 25C.