Recombinant Human Angiotensin-Converting Enzyme 2/ACE-2 (C-6His)
Catalog Number:
ABI-32-7375
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| Article Name: | Recombinant Human Angiotensin-Converting Enzyme 2/ACE-2 (C-6His) |
| Biozol Catalog Number: | ABI-32-7375 |
| Supplier Catalog Number: | 32-7375 |
| Alternative Catalog Number: | ABI-32-7375-50UG |
| Manufacturer: | Abeomics |
| Category: | Proteine/Peptide |
| Source: Human Cells. MW :84.63kD. Recombinant Human Angiotensin-Converting Enzyme 2 is produced by our Mammalian expression system and the target gene encoding Gln18-Ser740 is expressed with a 6His tag at the C-terminus. Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor dona€(TM)t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function. |
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