Recombinant Human Anthrax Toxin Receptor 1/ANTXR1/TEM8 (C-6His)

Product Overview

• Article Name: Recombinant Human Anthrax Toxin Receptor 1/ANTXR1/TEM8 (C-6His)
• Biozol Catalog Number: ABI-32-7764-10
• Supplier Catalog Number: 32-7764-10
• Alternative Catalog Number: ABI-32-7764-10-10UG
• Manufacturer: Abeomics
• Category: Proteine/Peptide

Product Description

Source: Human Cells. MW :33.56kD. Recombinant Human Anthrax Toxin Receptor 1 is produced by our Mammalian expression system and the target gene encoding Glu33-Lys321 is expressed with a 6His tag at the C-terminus. Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It is also involved in the angiogenic response of cultured umbilical vein endothelial cells, up-regulated in cultured angiogenic umbilical vein endothelial cells. Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI).

Product Properties

• NCBI: 84168
• UniProt: Q9H6X2
• Antibody Type: Recombinant Antibody

Application Notes

• Application Dilute: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freez