Recombinant Human Linker for Activation of T-Cells Family Member 2/LAT2 (C-6His)
Biozol Catalog Number:
ABI-32-7768
Supplier Catalog Number:
32-7768
Alternative Catalog Number:
ABI-32-7768-50UG
Manufacturer:
Abeomics
Category:
Proteine/Peptide
Source: Human Cells. MW :25kD. Recombinant Human Non-T cell activation linker is produced by our Mammalian expression system and the target gene encoding Arg27-Ala243 is expressed with a 6His tag at the C-terminus. Linker for Activation of T-Cells Family Member 2 (LAT2) is a single-pass type III membrane protein. LAT2 is highly expressed in the spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. LAT2 is involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. It may also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Coupleing activate of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2.
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freez
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