Recombinant Human IL-1 Receptor Accessory Protein/IL-1RAcP/IL-1R3 (C-Fc-6His)

Product Overview

• Article Name: Recombinant Human IL-1 Receptor Accessory Protein/IL-1RAcP/IL-1R3 (C-Fc-6His)
• Biozol Catalog Number: ABI-32-7811
• Supplier Catalog Number: 32-7811
• Alternative Catalog Number: ABI-32-7811-50UG
• Manufacturer: Abeomics
• Category: Proteine/Peptide

Product Description

Source: Human Cells. MW :39.7kD. Recombinant Human Interleukin-1 Receptor Accessory Protein is produced by our Mammalian expression system and the target gene encoding Ser21-Gln356 is expressed with a Fc, 6His tag at the C-terminus. Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the interleukin-1 receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-ligand binding accessory component of the receptors for IL1a, IL1 betaand IL33. IL-1RAcP mediates interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. In addition, IL-1RAcP modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor.

Product Properties

• NCBI: 3556
• UniProt: Q9NPH3
• Antibody Type: Recombinant Antibody

Application Notes

• Application Dilute: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freez