Recombinant Human Transcobalamin II Receptor/TCblR/8D6A/CD320 (C-6His)

Product Overview

• Article Name: Recombinant Human Transcobalamin II Receptor/TCblR/8D6A/CD320 (C-6His)
• Biozol Catalog Number: ABI-32-7856
• Supplier Catalog Number: 32-7856
• Alternative Catalog Number: ABI-32-7856-50UG
• Manufacturer: Abeomics
• Category: Proteine/Peptide

Product Description

Source: Human Cells. MW :21.1kD. Recombinant Human Transcobalamin II Receptor is produced by our Mammalian expression system and the target gene encoding Ser36-Val231 is expressed with a 6His tag at the C-terminus. CD320 antigen is also known as 8D6 antigen,FDC-signaling molecule 8D6,Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.

Product Properties

• NCBI: 51293
• UniProt: Q9NPF0
• Antibody Type: Recombinant Antibody

Application Notes

• Application Dilute: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freez