Recombinant Human Junctional Adhesion Molecule B/JAM-B/CD322 (C-Fc)

Product Overview

• Article Name: Recombinant Human Junctional Adhesion Molecule B/JAM-B/CD322 (C-Fc)
• Biozol Catalog Number: ABI-32-7891-10
• Supplier Catalog Number: 32-7891-10
• Alternative Catalog Number: ABI-32-7891-10-10UG
• Manufacturer: Abeomics
• Category: Proteine/Peptide

Product Description

Source: Human Cells. MW :50.3kD. Recombinant Human JAM-B is produced by our Mammalian expression system and the target gene encoding Phe29-Asn236 is expressed with a Fc tag at the C-terminus. Junctional Adhesion Molecule B (JAM-B) is a single-pass type I membrane protein that belongs to the juctional adhesion molecules family. JAM-B includes a signal sequence (aa 1-28), an extracellular region (aa 29-238) with one Ig-like C2-type domain and one Ig-like V-type domain, a transmembrane segment (aa 239-259), and a cytoplasmic domain (aa 260 - 298). JAMB is localized to the tight junctions between endothelial cells or epithelial cells. JAM-B is prominently expressed in the heart, placenta, lung, foreskin and lymph node. It is also present on the endothelia of other vessels. JAM-B acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.

Product Properties

• NCBI: 58494
• UniProt: P57087
• Antibody Type: Recombinant Antibody

Application Notes

• Application Dilute: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freez