Recombinant Human Bactericidal Permeability-Increasing Protein/BPI/CAP57 (C-6His)
Biozol Catalog Number:
ABI-32-7897-10
Supplier Catalog Number:
32-7897-10
Alternative Catalog Number:
ABI-32-7897-10-10UG
Manufacturer:
Abeomics
Category:
Proteine/Peptide
Source: Human Cells. MW :52.5kD. Recombinant Human CAP57 is produced by our Mammalian expression system and the target gene encoding Val32-Lys487 is expressed with a 6His tag at the C-terminus. Bactericidal permeability-increasing protein(BPI for short), is a secreted protein which belongs to the BPI/LBP/Plunc superfamily, BPI/LBP family. It exists as a monomer or a disulfide-linked homodimer. The cytotoxic action of BPI is limited to many species of Gram-negative bacteria. This specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. BPI has antibacterial activity against the Gram-nagative bacterium P.aeruginosa, and this activity is inhibited by LPS from P.aeruginosa.
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freez
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