Source: E.coli. MW :27.2kD. Recombinant Human Peroxiredoxin-6 is produced by our E.coli expression system and the target gene encoding Met1-Pro224 is expressed with a 6His tag at the N-terminus. Peroxiredoxin 6 belongs to the thiol-specific antioxidant protein family, which is a bifunctional enzyme with two distinct active sites. Peroxiredoxin 6 is involved in redox regulation of the cell and can reduce Hydrogen peroxide and short chain organic, fatty acid, and phospholipid hydroperoxides. Peroxiredoxin 6 may regulates phospholipid turnover and protectes against oxidative injury. Peroxiredoxin 6 eases the oxidative stress and TGF-beta-induced abnormalities of human trabecular meshwork cells, it is necessary for blood vessel integrity in injured skin.
