Source: E. coli. MW :43.2kD. Recombinant Human alpha-Parvin is produced by our E.coli expression system and the target gene encoding Met1-Glu372 is expressed with a 6His tag at the C-terminus. Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. PARVA may play a role in the regulation of cell adhesion and cytoskeleton organization. PARVA is also involved in ciliogenesis.
