Recombinant Human B-Cell Differentiation Antigen CD72/Lyb-2 (N-Trx, 6His)

Product Overview

• Article Name: Recombinant Human B-Cell Differentiation Antigen CD72/Lyb-2 (N-Trx, 6His)
• Biozol Catalog Number: ABI-32-8132-10
• Supplier Catalog Number: 32-8132-10
• Alternative Catalog Number: ABI-32-8132-10-10UG
• Manufacturer: Abeomics
• Category: Proteine/Peptide

Product Description

Source: E. coli. MW :30.6kD. Recombinant Human CD72 is produced by our E.coli expression system and the target gene encoding Arg117-Cys226 is expressed with a Trx, 6His tag at the N-terminus. B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulation and dampens BCR signaling through interactions with the phosphatase SHP-1.

Product Properties

• NCBI: 971
• UniProt: P21854
• Antibody Type: Recombinant Antibody

Application Notes

• Application Dilute: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freez