Recombinant Human UFM1-Activating Enzyme 5/UBA5 (N-6His)
Biozol Catalog Number:
ABI-32-8297-10
Supplier Catalog Number:
32-8297-10
Alternative Catalog Number:
ABI-32-8297-10-10UG
Manufacturer:
Abeomics
Category:
Proteine/Peptide
Source: E. coli. MW :47kD. Recombinant Human Ubiquitin-fold Modifier 1 Activating Enzyme is produced by our E.coli expression system and the target gene encoding Met1-Met404 is expressed with a 6His tag at the N-terminus. UBA5 is a member of the ubiquitin-activating E1 family and UBA5 subfamily. Ubiquitin and ubiquitin-like proteins are recognized as covalently conjugated to various cellular substrates by a three-step enzymatic pathway. The ubiquitin-activating enzyme (E1) has a vital role in the first step of ubiquitination pathway to activate ubiquitin or ubiquitin-like proteins. UBA5 activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. UBA5 is located primarily in cytoplasm, while it generally localizes to the nucleus in presence of SUMO2.
