Source: Human Cells. MW :47.9kD. Recombinant Mouse Testican-3 is produced by our Mammalian expression system and the target gene encoding Ala23-Ile436 is expressed with a 6His tag at the C-terminus. SPOCK3,also called Testican3,is a secreted protein and make up a family of extracellular heparan/chondroitin sulfate proteoglycans. It contains 1 Kazal-like domain and 1 thyroglobulin type-1 domain and mainly expressed in brain. SPOCK3 contain inhibitory regions in several domains targeted to different classes of protease, and in some cases may act as protease inhibitors. In addition to their presence in testis, testicans are enriched in brain and have been shown to regulate neuronal attachment and outgrowth.
