Recombinant Human Matrix Metalloproteinase-9/MMP-9 (C-6His)

Product Overview

• Article Name: Recombinant Human Matrix Metalloproteinase-9/MMP-9 (C-6His)
• Biozol Catalog Number: ABI-32-8451
• Supplier Catalog Number: 32-8451
• Alternative Catalog Number: ABI-32-8451-50UG
• Manufacturer: Abeomics
• Category: Proteine/Peptide

Product Description

Source: Human Cells. MW :77.4kD. Recombinant Human Matrix metalloproteinase-9 is produced by our Mammalian expression system and the target gene encoding Ala19-Asp707 is expressed with a 6His tag at the C-terminus. Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein, which is produced by normal alveolar macrophages and granulocytes, can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4, SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, angiogenesis, bone development, wound healing, cell migration, learning and memory, as well as in pathological processes, such as arthritis, intracerebral hemorrhage, and metastasis.

Product Properties

• NCBI: 4318
• UniProt: P14780
• Antibody Type: Recombinant Antibody

Application Notes

• Application Dilute: Endotoxin : Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test. Biological Activity : The specific activity is >1,100 pmol/min/µg. Measured by its ability to cleave the fluorogenic peptide substrate, Mca-PLGL-Dpa-AR-NH2 .