Recombinant Human NECTIN-4/PVRL4 (C-His)

Catalog Number: ABI-32-9034-500
Article Name: Recombinant Human NECTIN-4/PVRL4 (C-His)
Biozol Catalog Number: ABI-32-9034-500
Supplier Catalog Number: 32-9034-500
Alternative Catalog Number: ABI-32-9034-500-500UG
Manufacturer: Abeomics
Category: Proteine/Peptide
Alternative Names: Nectin cell adhesion molecule 4, Ig superfamily receptor LNIR, Poliovirus receptor-related protein 4, PVRL4, PRR4, LNIR
Source : Human 293 Cells,Nectin-4 (PVRL4) is a type I transmembrane glycoprotein that belongs to the nectin family of Ig superfamily proteins. Nectin-4 is expressed in the placenta, especially in endothelial cells. Nectin-4 ECD contains three Ig-like domains, including one N-terminal V-type and two C2-type. As cell adhesion molecules, Nectin-4 plays an important role in many biological processes during human development as well as adult life. Studies also showed that Nectin-4 acts as tumor-associated antigen in some of the breast, ovarian and non-small cell lung carcinomas, especially on those tumors with bad prognosis.
Antibody Type: Recombinant Antibody