Recombinant Human Insulin-like Growth Factor Binding Protein 3/IGFBP3 (C-hFc)
Biozol Catalog Number:
ABI-32-9088
Supplier Catalog Number:
32-9088
Alternative Catalog Number:
ABI-32-9088-50UG
Manufacturer:
Abeomics
Category:
Proteine/Peptide
Alternative Names:
acid stable subunit of the 140 K IGF complex, binding protein 29, binding protein 53, growth hormone-dependent binding protein, IBP-3, IBP3BP-53, IGF-binding protein 3, IGFBP3, IGFBP-3, insulin-like growth factor binding protein 3, insulin-like growth factor-binding protein 3
Source : Human 293 Cells, Insulin-like growth factor-binding protein 3 (IGFBP3) is a member of IGF binding protein superfamily. IGF binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth-promoting effects of the IGFs on cell culture. IGFBP3 is expressed by most tissues and the expression levels are higher during development. It is up-regulated in the presence of IGF1, insulin and other growth-stimulating factors such as growth hormone, EGF and phorbol esters. IGFBP3 is the most abundant IGF binding protein in human serum and has been shown to be a growth inhibitory, apoptosis-inducing molecule, capable of acting via IGF-dependent and IGF-independent mechanisms. Several clinical studies have shown that individuals with IGFBP3 levels in the upper range of normal may have a decreased risk for certain common cancers
Antibody Type:
Recombinant Antibody
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