Recombinant Human Neuronal Pentraxin-1/NPTX1 (C-6His)
Biozol Catalog Number:
ABI-32-9588
Supplier Catalog Number:
32-9588
Alternative Catalog Number:
ABI-32-9588-50UG
Manufacturer:
Abeomics
Category:
Proteine/Peptide
Alternative Names:
Neuronal pentraxin-1, NPTX1, NP1
Source : Human Cells,Neuronal Pentraxin (NPTX1, NP1) is a secreted glycoprotein within the Pentraxin family. NPTX1 is co-expressed and forms heteromultimers with the related secreted protein, NPTX2/NARP, NPTXR (Neuronal Pentraxin Receptor) at excitatory synapses. Mature human NPTX1 shares 97% aa sequence identity with mouse, and rat NPTX1. It is produced by hippocampal, cerebral and cerebellar neurons, retinal ganglia and the inner nuclear layer of the retina. It is enriched on presynaptic axonal membranes where it forms complexes with NPTXR. It may be involved in mediating uptake of synaptic material during synapse remodeling or in mediating the synaptic clustering of AMPA glutamate receptors at a subset of excitatory synapses.
Antibody Type:
Recombinant Antibody
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