Recombinant Human Intercellular Adhesion Molecule 1/ICAM-1/CD54 (C-Fc)
Biozol Catalog Number:
ABI-32-9684
Supplier Catalog Number:
32-9684
Alternative Catalog Number:
ABI-32-9684-50UG
Manufacturer:
Abeomics
Category:
Proteine/Peptide
Alternative Names:
Intercellular Adhesion Molecule 1, ICAM-1, Major Group Rhinovirus Receptor, CD54, ICAM1
Source : Human Cells,Inter-Cellular Adhesion Molecule 1 (ICAM1) is a type of intercellular adhesion molecule continuously present in low concentrations in the membranes of leukocytes and endothelial cells. As an endothelial and leukocyte-associated transmembrane protein, ICAM1 is well known for its importance in stabilizing cell-cell interactions and facilitating leukocyte endothelial transmigration. The presence of heavy glycosylation and other structural characteristics lend ICAM1 binding sites for a number of immune-associated ligands. Notably, ICAM-1 binds to macrophage adhesion ligand-1 (Mac-1, ITGB2 / ITGAM), leukocyte function associated antigen-1 (LFA-1/integrin), and fibrinogen.ICAM-1 expressed by respiratory epithelial cells is also the binding site for rhinovirus, the causative agent of most common colds.
Antibody Type:
Recombinant Antibody
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