Polyclonal Antibody to BCL-2(Phospho-Thr56), Rabbit
Biozol Catalog Number:
ABI-35-1062-50
Supplier Catalog Number:
35-1062-50
Alternative Catalog Number:
ABI-35-1062-50-50UL
Manufacturer:
Abeomics
Host:
Rabbit
Category:
Antikörper
Application:
IHC
Species Reactivity:
Human
Immunogen:
Peptide sequence around phosphorylation site of threonine 56(G-H-T(p)-P-H) derived from Human BCL-2.
Alternative Names:
Bcl-2||PPP1R50
Suppresses apoptosis in a variety of cell systems includingfactor-dependent lymphohematopoietic and neural cells. Regulates cell death bycontrolling the mitochondrial membrane permeability. Appears to function in a feedbackloop system with caspases. Inhibits caspase activity either by preventing the release ofcytochrome c from the mitochondria and/or by binding to the apoptosis-activatingfactor (APAF-1).